IVF with PGD for Gender Selection in Turkey, Find the Best Option

Le 2 July 2024

In vitro fertilization (IVF) combined with preimplantation genetic diagnosis (PGD) has become a sought-after solution for couples looking to select the sex of their baby.

This advanced reproductive technology not only helps in preventing genetic disorders but also allows parents to choose the gender of their child.

Turkey has emerged as a popular destination for this procedure due to its high-quality medical services and comparatively lower costs.

Understanding IVF and PGD

IVF Process:

In vitro fertilization is a process where eggs are retrieved from the ovaries and fertilized by sperm in a laboratory.

The resulting embryos are then transferred to the uterus. The main steps of IVF include ovarian stimulation, egg retrieval, fertilization, and embryo transfer.

PGD Process:

Preimplantation genetic diagnosis involves screening embryos for genetic disorders and chromosomal abnormalities before implantation.

This procedure is performed alongside IVF. A few cells are biopsied from the embryos, and genetic analysis is conducted to determine their genetic makeup, including sex chromosomes.

Why Choose Turkey for IVF with PGD?

Affordability:

Turkey offers significantly lower costs for IVF with PGD compared to countries like the United States, the United Kingdom, and other Western nations.

The overall cost savings can be substantial, making Turkey an attractive option for international patients.

High-Quality Medical Services:

Turkish fertility clinics are known for their high standards of care, experienced medical professionals, and advanced technology. Many clinics are accredited by international organizations, ensuring quality and safety.

Success Rates:

The success rates of IVF with PGD in Turkey are comparable to those in Western countries. Clinics in Turkey report high success rates, providing reassurance to patients seeking effective treatment.

Comprehensive Care:

Clinics in Turkey offer comprehensive care, including personalized treatment plans, counseling, and support throughout the entire process. Patients receive dedicated attention and guidance from experienced professionals.

Prices of all types of the IVF with PGD for Gender Selection in Turkey.

Standard IVF with PGD for Gender Selection

Definition and Details:

Standard IVF with PGD for gender selection involves several meticulously planned steps aimed at ensuring successful fertilization and implantation of embryos of the desired gender. The process starts with ovarian stimulation, which involves administering gonadotropins to stimulate the ovaries to produce multiple eggs.

This phase typically lasts about 10-14 days, during which the patient’s response is monitored through blood tests and ultrasounds to adjust medication dosages if necessary.

Once the follicles reach the appropriate size, a trigger shot of human chorionic gonadotropin (hCG) is administered to mature the eggs.

Egg retrieval is performed approximately 36 hours later under mild sedation. The eggs are then fertilized with sperm in a laboratory setting using traditional insemination or Intracytoplasmic Sperm Injection (ICSI), where a single sperm is injected directly into an egg.

Embryos are cultured for 3 to 5 days, reaching the blastocyst stage. At this point, a few cells are biopsied from each embryo.

These cells are analyzed for chromosomal abnormalities and to determine the sex of the embryos. Only embryos of the desired gender and without genetic abnormalities are selected for transfer.

The embryo transfer involves placing one or more selected embryos into the woman’s uterus, a procedure that is quick and usually pain-free.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
PGD Testing: $2,000 – $4,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $8,000 – $14,000

IVF with Preimplantation Genetic Screening (PGS) for Gender Selection

Definition and Details:

Preimplantation Genetic Screening (PGS) is an advanced form of PGD that screens all 23 pairs of chromosomes in the embryos.

This comprehensive screening not only identifies the sex of the embryos but also detects chromosomal abnormalities such as aneuploidies (extra or missing chromosomes) that could lead to conditions like Down syndrome, Turner syndrome, and other genetic disorders.

PGS is often recommended for older women, couples with a history of miscarriages, or those with known genetic issues.

The process of IVF with PGS for gender selection begins with ovarian stimulation to produce multiple eggs, which are retrieved and fertilized. The resulting embryos are cultured until they reach the blastocyst stage.

A biopsy is then performed to obtain cells for genetic analysis. The genetic material from these cells is amplified and analyzed using next-generation sequencing (NGS) or array comparative genomic hybridization (aCGH).

PGS provides a detailed chromosomal map of each embryo, allowing the selection of embryos with the correct number of chromosomes and the desired sex.

This reduces the risk of miscarriage and increases the chances of a healthy pregnancy. The selected embryos are then transferred to the uterus.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
PGS Testing: $2,500 – $5,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $9,000 – $15,000

IVF with Comprehensive Chromosomal Screening (CCS) for Gender Selection

Definition and Details:

Comprehensive Chromosomal Screening (CCS) is similar to PGS but involves an even more detailed analysis of all chromosomes.

This technique ensures that only embryos with the correct chromosomal number and desired gender are selected. CCS is beneficial for couples with recurrent implantation failure, unexplained infertility, or a history of genetic disorders.

The process involves the standard IVF steps: ovarian stimulation, egg retrieval, and fertilization. Embryos are cultured to the blastocyst stage, and a biopsy is taken. CCS uses advanced techniques like NGS to examine each chromosome thoroughly.

This detailed screening helps in identifying the best quality embryos with the desired gender, ensuring a higher success rate for implantation and pregnancy.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
CCS Testing: $3,000 – $5,500
Embryo Transfer: $1,000 – $1,500
Total Cost: $10,000 – $16,500

IVF with Next-Generation Sequencing (NGS) for Gender Selection

Definition and Details:

Next-Generation Sequencing (NGS) is a cutting-edge technology used in PGD for an in-depth analysis of the genetic makeup of embryos.

NGS allows for the sequencing of entire genomes, providing detailed information about the chromosomal status and genetic health of each embryo.

This method ensures the highest level of accuracy in selecting embryos of the desired gender and free from genetic abnormalities.

The IVF process with NGS involves ovarian stimulation, egg retrieval, fertilization, and embryo culture. A biopsy is taken from the embryos at the blastocyst stage, and NGS is performed on the genetic material extracted from these cells.

NGS can detect even the smallest genetic mutations and abnormalities, offering a comprehensive analysis that guides the selection of the best embryos for transfer.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
NGS Testing: $3,000 – $5,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $10,000 – $15,000

IVF with Single Gene Disorder Testing (SGDT) and Gender Selection

Definition and Details:

Single Gene Disorder Testing (SGDT) is a type of PGD used to detect specific genetic mutations that cause single-gene disorders, such as cystic fibrosis, sickle cell anemia, and Huntington’s disease. This method is ideal for couples at risk of passing on a genetic disorder and who also wish to select the gender of their child.

The process starts with ovarian stimulation, egg retrieval, and fertilization. Embryos are cultured to the blastocyst stage, and a biopsy is performed.

Genetic material from the biopsied cells is analyzed to identify the presence of specific gene mutations. This analysis also includes determining the sex of the embryos.

Only embryos without the targeted genetic disorder and of the desired gender are selected for transfer.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
SGDT Testing: $3,000 – $5,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $9,000 – $14,500

IVF with Human Leukocyte Antigen (HLA) Matching and Gender Selection

Definition and Details:

Human Leukocyte Antigen (HLA) matching in conjunction with IVF and PGD is used primarily for families who require an HLA-matched sibling for a sick child in need of a stem cell transplant. This procedure also allows for gender selection.

HLA matching involves selecting embryos with a genetic profile that is compatible with the sick sibling, ensuring they can serve as a stem cell donor.

The IVF process involves ovarian stimulation, egg retrieval, and fertilization. Embryos are cultured to the blastocyst stage, and a biopsy is performed. The genetic material is analyzed for HLA compatibility and sex determination. Only HLA-matched embryos of the desired gender are selected for transfer.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
HLA Matching and PGD Testing: $3,500 – $5,500
Embryo Transfer: $1,000 – $1,500
Total Cost: $10,500 – $16,500

IVF with Embryo Biopsy at Cleavage Stage and Gender Selection

Definition and Details:

Embryo biopsy at the cleavage stage involves extracting a cell from an embryo on the third day of development, when the embryo consists of around 6-8 cells. This method allows for early genetic testing and gender determination.

The biopsy is less invasive compared to later-stage biopsies, but it requires highly skilled embryologists to ensure embryo viability is not compromised.

After ovarian stimulation and egg retrieval, fertilization is carried out, and embryos are cultured to the cleavage stage.

A single cell is then biopsied from each embryo and analyzed for genetic content, including the determination of sex. Only embryos of the desired gender are selected for transfer into the uterus.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
Cleavage Stage PGD Testing: $2,000 – $3,500
Embryo Transfer: $1,000 – $1,500
Total Cost: $8,000 – $13,500

IVF with Blastocyst Biopsy and Gender Selection

Definition and Details:

Blastocyst biopsy is a technique where embryos are cultured for 5-6 days until they reach the blastocyst stage, consisting of about 100 cells.

At this stage, a few cells from the outer layer (trophectoderm) are biopsied for genetic analysis, including gender determination.

This method is advantageous as it involves more cells for testing, which increases the accuracy of results and reduces the risk of damaging the embryo.

The process includes ovarian stimulation, egg retrieval, fertilization, and culture to the blastocyst stage. The biopsy is performed, and the cells are analyzed for genetic abnormalities and sex. Only healthy embryos of the desired gender are selected for transfer.

Pricing:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
Blastocyst Stage PGD Testing: $2,500 – $4,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $9,500 – $14,000

IVF with Embryo Banking and Gender Selection

Definition and Details:

Embryo banking involves multiple cycles of IVF to create and store a large number of embryos, which are then genetically tested and selected for gender.

This approach is suitable for couples who want to maximize their chances of successful pregnancy by having a larger pool of embryos to choose from.

Embryo banking allows for the collection of eggs and creation of embryos over several cycles, followed by freezing (cryopreservation) until a sufficient number of embryos are available for PGD.

The process includes ovarian stimulation, egg retrieval, and fertilization over multiple cycles. Embryos are cultured to the blastocyst stage, biopsied, and tested for genetic abnormalities and gender. Only embryos of the desired gender are selected for transfer in a subsequent cycle.

Pricing:

Ovarian Stimulation (per cycle): $1,000 – $2,500
Egg Retrieval (per cycle): $1,500 – $2,000
ICSI (per cycle): $1,000 – $1,500
Embryo Culture and Biopsy (per cycle): $1,500 – $2,500
Embryo Freezing (per cycle): $500 – $1,000
PGD Testing (per cycle): $2,000 – $4,000
Embryo Transfer: $1,000 – $1,500
Total Cost (per cycle): $8,000 – $14,000
Total Cost (multiple cycles): $16,000 – $28,000

IVF with Minimal Stimulation and PGD for Gender Selection

Definition and Details:

Minimal stimulation IVF, also known as mini-IVF or mild IVF, uses lower doses of fertility drugs to stimulate the ovaries, resulting in fewer but potentially higher-quality eggs.

This approach is less invasive, less costly, and reduces the risk of ovarian hyperstimulation syndrome (OHSS).

It’s particularly suitable for women who respond poorly to standard ovarian stimulation or those who prefer a gentler approach.

The process involves administering low doses of fertility drugs to stimulate the ovaries, followed by egg retrieval and fertilization. Embryos are cultured to the blastocyst stage, and a biopsy is performed.

The biopsied cells are analyzed for genetic content, including gender determination. Only embryos of the desired gender are selected for transfer.

Pricing:

Ovarian Stimulation: $500 – $1,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
PGD Testing: $2,000 – $4,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $7,500 – $13,000

Price Analysis of IVF PGD for Gender Selection in Istanbul, Ankara, and Izmir

Standard IVF with PGD for Gender Selection

Istanbul:

Ovarian Stimulation: $1,200 – $2,800
Egg Retrieval: $1,600 – $2,200
ICSI: $1,200 – $1,800
Embryo Culture and Biopsy: $1,800 – $2,800
PGD Testing: $2,200 – $4,500
Embryo Transfer: $1,200 – $1,700
Total Cost: $9,200 – $15,800

Ankara:

Ovarian Stimulation: $1,100 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,100 – $1,600
Embryo Culture and Biopsy: $1,600 – $2,400
PGD Testing: $2,000 – $4,200
Embryo Transfer: $1,100 – $1,600
Total Cost: $8,400 – $14,300

Izmir:

Ovarian Stimulation: $1,000 – $2,300
Egg Retrieval: $1,400 – $1,900
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,300
PGD Testing: $1,800 – $4,000
Embryo Transfer: $1,000 – $1,500
Total Cost: $7,700 – $13,500

IVF with Preimplantation Genetic Screening (PGS) for Gender Selection

Istanbul:

Ovarian Stimulation: $1,300 – $2,900
Egg Retrieval: $1,700 – $2,300
ICSI: $1,300 – $1,900
Embryo Culture and Biopsy: $1,900 – $2,900
PGS Testing: $2,700 – $5,200
Embryo Transfer: $1,300 – $1,800
Total Cost: $10,200 – $17,000

Ankara:

Ovarian Stimulation: $1,200 – $2,600
Egg Retrieval: $1,600 – $2,100
ICSI: $1,200 – $1,700
Embryo Culture and Biopsy: $1,700 – $2,500
PGS Testing: $2,500 – $5,000
Embryo Transfer: $1,200 – $1,700
Total Cost: $9,200 – $15,600

Izmir:

Ovarian Stimulation: $1,100 – $2,400
Egg Retrieval: $1,500 – $2,000
ICSI: $1,100 – $1,600
Embryo Culture and Biopsy: $1,600 – $2,400
PGS Testing: $2,300 – $4,800
Embryo Transfer: $1,100 – $1,600
Total Cost: $8,700 – $14,800

IVF with Comprehensive Chromosomal Screening (CCS) for Gender Selection

Istanbul:

Ovarian Stimulation: $1,400 – $3,000
Egg Retrieval: $1,800 – $2,400
ICSI: $1,400 – $2,000
Embryo Culture and Biopsy: $2,000 – $3,000
CCS Testing: $3,200 – $5,700
Embryo Transfer: $1,400 – $1,900
Total Cost: $11,200 – $18,000

Ankara:

Ovarian Stimulation: $1,300 – $2,700
Egg Retrieval: $1,700 – $2,200
ICSI: $1,300 – $1,800
Embryo Culture and Biopsy: $1,800 – $2,600
CCS Testing: $3,000 – $5,500
Embryo Transfer: $1,300 – $1,800
Total Cost: $10,400 – $16,600

Izmir:

Ovarian Stimulation: $1,200 – $2,500
Egg Retrieval: $1,600 – $2,100
ICSI: $1,200 – $1,700
Embryo Culture and Biopsy: $1,700 – $2,500
CCS Testing: $2,800 – $5,300
Embryo Transfer: $1,200 – $1,700
Total Cost: $9,700 – $15,800

IVF with Next-Generation Sequencing (NGS) for Gender Selection

Istanbul:

Ovarian Stimulation: $1,500 – $3,100
Egg Retrieval: $1,900 – $2,500
ICSI: $1,500 – $2,100
Embryo Culture and Biopsy: $2,100 – $3,100
NGS Testing: $3,500 – $5,800
Embryo Transfer: $1,500 – $2,000
Total Cost: $11,900 – $18,600

Ankara:

Ovarian Stimulation: $1,400 – $2,800
Egg Retrieval: $1,800 – $2,300
ICSI: $1,400 – $1,900
Embryo Culture and Biopsy: $1,900 – $2,700
NGS Testing: $3,300 – $5,500
Embryo Transfer: $1,400 – $1,900
Total Cost: $10,900 – $17,100

Izmir:

Ovarian Stimulation: $1,300 – $2,600
Egg Retrieval: $1,700 – $2,200
ICSI: $1,300 – $1,800
Embryo Culture and Biopsy: $1,800 – $2,600
NGS Testing: $3,100 – $5,300
Embryo Transfer: $1,300 – $1,800
Total Cost: $10,500 – $16,300

IVF with Single Gene Disorder Testing (SGDT) and Gender Selection

Istanbul:

Ovarian Stimulation: $1,600 – $3,200
Egg Retrieval: $2,000 – $2,600
ICSI: $1,600 – $2,200
Embryo Culture and Biopsy: $2,200 – $3,200
SGDT Testing: $3,700 – $6,200
Embryo Transfer: $1,600 – $2,100
Total Cost: $12,700 – $19,500

Ankara:

Ovarian Stimulation: $1,500 – $2,900
Egg Retrieval: $1,900 – $2,400
ICSI: $1,500 – $2,000
Embryo Culture and Biopsy: $2,000 – $2,800
SGDT Testing: $3,500 – $6,000
Embryo Transfer: $1,500 – $2,000
Total Cost: $11,900 – $18,100

Izmir:

Ovarian Stimulation: $1,400 – $2,700
Egg Retrieval: $1,800 – $2,300
ICSI: $1,400 – $1,900
Embryo Culture and Biopsy: $1,900 – $2,700
SGDT Testing: $3,300 – $5,800
Embryo Transfer: $1,400 – $1,900
Total Cost: $11,200 – $17,300

IVF with Array Comparative Genomic Hybridization (aCGH) for Gender Selection

Istanbul:

Ovarian Stimulation: $1,700 – $3,300
Egg Retrieval: $2,100 – $2,700
ICSI: $1,700 – $2,300
Embryo Culture and Biopsy: $2,300 – $3,300
aCGH Testing: $4,000 – $6,500
Embryo Transfer: $1,700 – $2,200
Total Cost: $13,500 – $20,300

Ankara:

Ovarian Stimulation: $1,600 – $3,000
Egg Retrieval: $2,000 – $2,500
ICSI: $1,600 – $2,100
Embryo Culture and Biopsy: $2,100 – $2,900
aCGH Testing: $3,800 – $6,300
Embryo Transfer: $1,600 – $2,100
Total Cost: $12,700 – $18,900

Izmir:

Ovarian Stimulation: $1,500 – $2,800
Egg Retrieval: $1,900 – $2,400
ICSI: $1,500 – $2,000
Embryo Culture and Biopsy: $2,000 – $2,800
aCGH Testing: $3,600 – $6,000
Embryo Transfer: $1,500 – $2,000
Total Cost: $11,900 – $17,800

IVF with Cleavage Stage Biopsy and Gender Selection

Istanbul:

Ovarian Stimulation: $1,000 – $2,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,500
Cleavage Stage PGD Testing: $2,000 – $3,500
Embryo Transfer: $1,000 – $1,500
Total Cost: $8,000 – $13,500

Ankara:

Ovarian Stimulation: $900 – $2,300
Egg Retrieval: $1,400 – $1,900
ICSI: $900 – $1,400
Embryo Culture and Biopsy: $1,400 – $2,300
Cleavage Stage PGD Testing: $1,800 – $3,300
Embryo Transfer: $900 – $1,400
Total Cost: $7,300 – $12,600

Izmir:

Ovarian Stimulation: $800 – $2,100
Egg Retrieval: $1,300 – $1,800
ICSI: $800 – $1,300
Embryo Culture and Biopsy: $1,300 – $2,100
Cleavage Stage PGD Testing: $1,600 – $3,000
Embryo Transfer: $800 – $1,300
Total Cost: $6,600 – $11,600

IVF with Blastocyst Biopsy and Gender Selection

Istanbul:

Ovarian Stimulation: $1,200 – $2,800
Egg Retrieval: $1,600 – $2,200
ICSI: $1,200 – $1,800
Embryo Culture and Biopsy: $1,800 – $2,800
Blastocyst Stage PGD Testing: $2,500 – $4,000
Embryo Transfer: $1,200 – $1,700
Total Cost: $9,500 – $14,000

Ankara:

Ovarian Stimulation: $1,100 – $2,600
Egg Retrieval: $1,500 – $2,000
ICSI: $1,100 – $1,600
Embryo Culture and Biopsy: $1,600 – $2,500
Blastocyst Stage PGD Testing: $2,300 – $3,800
Embryo Transfer: $1,100 – $1,600
Total Cost: $8,700 – $13,500

Izmir:

Ovarian Stimulation: $1,000 – $2,400
Egg Retrieval: $1,400 – $1,900
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,300
Blastocyst Stage PGD Testing: $2,000 – $3,500
Embryo Transfer: $1,000 – $1,500
Total Cost: $7,900 – $12,600

IVF with Embryo Banking and Gender Selection

Istanbul:

Ovarian Stimulation (per cycle): $1,200 – $2,800
Egg Retrieval (per cycle): $1,600 – $2,200
ICSI (per cycle): $1,200 – $1,800
Embryo Culture and Biopsy (per cycle): $1,800 – $2,800
Embryo Freezing (per cycle): $600 – $1,200
PGD Testing (per cycle): $2,500 – $4,500
Embryo Transfer: $1,200 – $1,700
Total Cost (per cycle): $9,100 – $17,000
Total Cost (multiple cycles): $18,200 – $34,000

Ankara:

Ovarian Stimulation (per cycle): $1,100 – $2,600
Egg Retrieval (per cycle): $1,500 – $2,000
ICSI (per cycle): $1,100 – $1,600
Embryo Culture and Biopsy (per cycle): $1,600 – $2,500
Embryo Freezing (per cycle): $500 – $1,100
PGD Testing (per cycle): $2,300 – $4,200
Embryo Transfer: $1,100 – $1,600
Total Cost (per cycle): $8,200 – $15,000
Total Cost (multiple cycles): $16,400 – $30,000

Izmir:

Ovarian Stimulation (per cycle): $1,000 – $2,400
Egg Retrieval (per cycle): $1,400 – $1,900
ICSI (per cycle): $1,000 – $1,500
Embryo Culture and Biopsy (per cycle): $1,500 – $2,300
Embryo Freezing (per cycle): $500 – $1,000
PGD Testing (per cycle): $2,000 – $3,800
Embryo Transfer: $1,000 – $1,500
Total Cost (per cycle): $7,400 – $13,900
Total Cost (multiple cycles): $14,800 – $27,800

IVF with Minimal Stimulation and PGD for Gender Selection

Istanbul:

Ovarian Stimulation: $600 – $1,600
Egg Retrieval: $1,600 – $2,200
ICSI: $1,200 – $1,800
Embryo Culture and Biopsy: $1,800 – $2,800
PGD Testing: $2,500 – $4,500
Embryo Transfer: $1,200 – $1,700
Total Cost: $8,900 – $14,600

Ankara:

Ovarian Stimulation: $500 – $1,500
Egg Retrieval: $1,500 – $2,000
ICSI: $1,100 – $1,600
Embryo Culture and Biopsy: $1,600 – $2,500
PGD Testing: $2,300 – $4,200
Embryo Transfer: $1,100 – $1,600
Total Cost: $8,100 – $13,400

Izmir:

Ovarian Stimulation: $400 – $1,400
Egg Retrieval: $1,400 – $1,900
ICSI: $1,000 – $1,500
Embryo Culture and Biopsy: $1,500 – $2,300
PGD Testing: $2,000 – $3,800
Embryo Transfer: $1,000 – $1,500
Total Cost: $7,300 – $12,400

Factors Influencing the Cost of IVF with PGD in Turkey

Clinic Reputation and Location:

Clinics in major cities like Istanbul, Ankara, and Izmir tend to have higher costs due to their reputation and the availability of advanced medical technology.

However, they also offer higher success rates and more experienced medical teams.

Medical Team Expertise:

The expertise and experience of the fertility specialists, embryologists, and geneticists play a crucial role in the success of IVF with PGD.

Clinics with renowned specialists may charge higher fees.

Technology and Equipment:

The use of advanced technology and state-of-the-art equipment can impact the overall cost. Clinics investing in the latest medical advancements may have higher fees but offer better success rates and safety.

Patient-Specific Factors:

Each patient’s medical condition and history can influence the cost. Factors such as age, ovarian reserve, and the need for additional treatments or medications can affect the overall expenses.

Additional Considerations for Patients

Legal and Ethical Aspects:

It’s essential to understand the legal and ethical aspects of gender selection in Turkey. While PGD for medical reasons is widely accepted, gender selection for non-medical reasons may have specific regulations.

Travel and Accommodation:

Patients traveling to Turkey for IVF with PGD should consider travel and accommodation expenses. Many clinics offer packages that include assistance with travel arrangements, accommodation, and local transportation.

Language and Communication:

English is widely spoken in Turkish medical facilities, ensuring effective communication between patients and medical staff. Clinics often have multilingual staff to assist international patients.

Cultural and Tourism Opportunities:

Turkey offers a rich cultural experience and numerous tourist attractions. Patients can combine their medical journey with a memorable vacation, exploring historical sites, beautiful landscapes, and vibrant cities.

Preparations Before Undergoing IVF with Gender Selection in Turkey

Personal Preparations:

Understanding the Procedure:

IVF with gender selection combines in vitro fertilization (IVF) techniques with genetic testing to identify embryos of a desired gender before implantation.

Research the procedure thoroughly to understand its steps, potential outcomes, and associated risks such as multiple pregnancies or ovarian hyperstimulation syndrome (OHSS).

Discuss the procedure with your partner to ensure mutual understanding and support throughout the process, addressing any concerns or expectations.

Emotional Preparation:

Acknowledge and prepare for the emotional challenges that often accompany fertility treatments like IVF.

Recognize that IVF can be a physically and emotionally demanding journey. Consider seeking counseling or joining support groups specialized in fertility to cope with stress, anxiety, and disappointment.

Maintain open communication with your partner to navigate emotional ups and downs together, fostering a supportive environment.

Lifestyle Changes:

Adopt a healthy lifestyle to optimize fertility potential. Focus on a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to provide essential nutrients.

Limit caffeine intake and avoid smoking, excessive alcohol consumption, and recreational drug use, as these can negatively impact fertility and the success of IVF treatments.

Engage in regular physical activity such as walking, yoga, or swimming to manage stress levels, improve overall fitness, and enhance well-being.

Physical Fitness:

Prioritize physical fitness as part of preparation for IVF. Consult with a healthcare provider or fitness expert to develop a suitable exercise regimen tailored to your needs and current fitness level.

Aim for moderate exercise routines that promote cardiovascular health, muscle strength, and flexibility, avoiding strenuous activities that may negatively affect reproductive health.

Financial Planning:

Assess the financial implications of IVF with gender selection, including procedure costs, medications, genetic testing fees, and potential additional cycles.

Research insurance coverage options for fertility treatments and inquire about financial assistance programs or payment plans offered by fertility clinics.

Create a budget and financial plan to manage expenses associated with IVF, ensuring transparency and clarity regarding financial commitments throughout the treatment process.

Support System:

Build a strong support network of family members, friends, or support groups who understand and empathize with your journey through IVF.

Communicate openly with loved ones about your decision to undergo IVF with gender selection, sharing information about the procedure and how they can provide practical assistance and emotional support.

Consider attending fertility support groups or online forums to connect with others experiencing similar challenges, exchanging insights, and gaining reassurance from shared experiences.

Preparations with the Doctor:

Medical Evaluation:

Schedule a comprehensive medical evaluation with a fertility specialist to assess reproductive health, identify potential fertility issues, and determine the most suitable treatment plan.

Undergo diagnostic tests such as blood tests, semen analysis (if applicable), ultrasound scans, and a hysterosalpingogram (HSG) to evaluate ovarian reserve, uterine health, and fallopian tube patency.

Discuss medical history, previous fertility treatments, and any existing health conditions or medications that may impact fertility or IVF outcomes.

Collaborate with your fertility specialist to develop a personalized treatment protocol based on diagnostic results, optimizing the chances of successful IVF with gender selection.

Genetic Counseling and Testing:

Consult with a genetic counselor to understand the implications of genetic testing and gender selection within the context of IVF.

Discuss the available genetic screening methods, including preimplantation genetic testing for aneuploidy (PGT-A) and preimplantation genetic testing for monogenic/single gene defects (PGT-M).

Review the ethical considerations, legal regulations, and societal implications associated with gender selection, ensuring informed decision-making and understanding the limitations of genetic testing technology.

Treatment Plan and Protocol:

Collaborate with your fertility specialist to outline a detailed treatment plan and protocol for IVF with gender selection, incorporating ovarian stimulation medications, egg retrieval procedures, embryo culture, genetic testing, and embryo transfer.

Review the timeline for each treatment phase, including medication schedules, monitoring appointments, and anticipated dates for egg retrieval and embryo transfer.

Discuss contingency plans for unexpected challenges or changes in treatment protocol, maintaining flexibility while prioritizing your reproductive health and treatment goals.

Medication Administration and Monitoring:

Receive personalized instructions on administering fertility medications, including injections or oral medications used to stimulate ovarian follicle growth and regulate ovulation.

Attend monitoring appointments at the fertility clinic to assess ovarian response to medications, monitor hormone levels, and adjust treatment protocols as needed based on ultrasound scans and blood test results.

Communicate any concerns or side effects related to fertility medications promptly with your fertility specialist, ensuring comprehensive support and medical guidance throughout the treatment cycle.

Psychological Support and Counseling:

Engage in psychological counseling sessions to address emotional challenges, fears, or anxieties related to IVF with gender selection.

Discuss coping strategies, stress management techniques, and mindfulness practices to promote emotional well-being and resilience during the treatment journey.

Utilize resources provided by the fertility clinic, such as counseling services or mental health professionals specializing in reproductive medicine, to enhance psychological support and holistic care.

Logistical Planning:

Coordinate logistical arrangements for travel to and from the fertility clinic, accommodation during treatment cycles, and transportation to medical appointments.

Prepare a contingency plan for unforeseen circumstances, such as weather disruptions, transportation delays, or unexpected changes in treatment schedule, to minimize stress and ensure continuity of care.

Compile essential contact information for the fertility clinic, emergency medical services, and support networks, maintaining clear communication channels throughout the treatment process.

The Steps During IVF with Gender Selection Procedure

Ovarian Stimulation:

Purpose: Ovarian stimulation aims to encourage the ovaries to produce multiple eggs simultaneously, increasing the chances of successful fertilization and embryo development.

Procedure:

Initial Consultation: Your fertility specialist will conduct a thorough medical evaluation to assess your reproductive health and discuss the IVF procedure, including ovarian stimulation.
Hormone Medications: You will begin treatment with gonadotropin medications, often administered through daily injections over a period of 8 to 14 days. These medications stimulate the ovaries to develop multiple follicles, each containing an egg.
Monitoring: Regular monitoring is essential during ovarian stimulation. Transvaginal ultrasound scans and blood tests are performed to assess follicle growth and hormone levels. The frequency of monitoring appointments may vary based on individual response to medications.
Adjustments: Based on monitoring results, your fertility specialist may adjust the dosage and type of medications to optimize egg production and ensure a balanced response from the ovaries.

Egg Retrieval (Oocyte Retrieval):

Purpose: Egg retrieval is a minimally invasive surgical procedure performed to retrieve mature eggs from the ovaries for fertilization in the laboratory.

Procedure:

Trigger Shot: Once monitoring indicates that the follicles are mature, you will receive a trigger shot of human chorionic gonadotropin (hCG) to induce final egg maturation, typically about 36 hours before egg retrieval.
Sedation or Anesthesia: Egg retrieval is performed under sedation or anesthesia to ensure your comfort during the procedure. It is usually a short outpatient procedure lasting approximately 20-30 minutes.
Guided Retrieval: Using transvaginal ultrasound guidance, a thin needle is inserted through the vaginal wall and into each ovarian follicle. The fluid containing the mature eggs is gently aspirated and collected in a sterile container.
Immediate Processing: The collected eggs are immediately taken to the laboratory for evaluation and preparation for fertilization.

Sperm Collection and Preparation:

Purpose: Sperm collection and preparation involve obtaining a high-quality sperm sample and preparing it for fertilizing the retrieved eggs in the laboratory.

Procedure:

Sperm Collection: On the day of egg retrieval, the male partner provides a semen sample through masturbation. The sample is collected in a sterile container and delivered to the laboratory.
Sperm Processing: The semen sample undergoes sperm processing techniques to isolate motile sperm from seminal fluid and debris. Methods may include density gradient centrifugation or swim-up techniques to enhance sperm quality and concentration.
Quality Assessment: Sperm quality and quantity are assessed to ensure optimal conditions for fertilization. The most motile and viable sperm are selected for use in the IVF procedure.

Fertilization:

Purpose: Fertilization involves the union of the retrieved eggs with sperm to form embryos in the laboratory setting.

Procedure:

Fertilization Methods: Depending on the specific circumstances, fertilization can occur through conventional IVF or intracytoplasmic sperm injection (ICSI). In conventional IVF, eggs and sperm are combined in a culture dish and incubated together, allowing natural fertilization to occur. ICSI involves injecting a single sperm directly into each mature egg to facilitate fertilization in cases of male factor infertility or previous IVF failure.
Incubation: Fertilized eggs (embryos) are cultured in a specialized incubator that maintains optimal temperature, humidity, and gas concentration. This controlled environment supports embryo development and allows for continuous monitoring.
Monitoring Development: Embryo development is monitored closely over the next few days to assess cell division and progression towards the blastocyst stage, which typically occurs by day 5 or 6 after fertilization.

Embryo Culture:

Purpose: Embryo culture involves nurturing fertilized eggs (embryos) in the laboratory until they reach an optimal stage for genetic testing or embryo transfer.

Procedure:

Optimal Conditions: Embryos are cultured in a culture medium that mimics the natural environment of the female reproductive tract. The culture dish is placed in a specialized incubator with controlled conditions of temperature, humidity, and gas composition to support optimal embryo development.
Developmental Assessment: Throughout the culture period, embryos are assessed for their developmental progress, including the number of cells, symmetry of division, and potential to reach the blastocyst stage. This assessment helps determine the quality and viability of embryos for subsequent procedures.

Genetic Testing (PGD/PGS):

Purpose: Genetic testing, also known as preimplantation genetic diagnosis (PGD) or preimplantation genetic screening (PGS), is performed to identify genetic abnormalities or chromosomal disorders in embryos and, in the case of PGD, to determine gender.

Procedure:

Biopsy Procedure: A small number of cells (blastomeres) are carefully removed from each embryo on day 3 or from trophectoderm cells of blastocysts on day 5-6.
Genetic Analysis: The biopsied cells undergo genetic analysis using advanced technologies such as fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), or next-generation sequencing (NGS). This analysis detects chromosomal abnormalities (PGS) or specific genetic conditions (PGD).
Gender Determination: In cases where gender selection is desired, PGD is used to identify embryos of the desired gender. The results of genetic testing help fertility specialists select healthy embryos with the correct genetic profile for transfer.
Reporting Results: Results of genetic testing are typically available within a few days, allowing fertility specialists to proceed with embryo selection for transfer based on the genetic profile and health status of each embryo.

Embryo Transfer:

Purpose: Embryo transfer involves placing selected embryos into the woman’s uterus to facilitate implantation and pregnancy.

Procedure:

Timing: Embryo transfer is typically performed on day 3 or day 5-6 after fertilization, depending on embryo development and genetic testing results.
Preparation: Prior to embryo transfer, the woman’s uterus may be prepared with hormonal medications or natural cycle monitoring to optimize endometrial receptivity.
Transfer Process: A thin, flexible catheter containing the selected embryos is inserted through the cervix and into the uterine cavity under ultrasound guidance.
Placement: The embryos are gently deposited into the uterus. The number of embryos transferred is based on factors such as patient age, embryo quality, and previous IVF outcomes.
Post-Transfer Care: After embryo transfer, the woman may be advised to rest briefly before resuming normal activities. Additional hormonal support may be provided to support early embryo development and implantation.

Luteal Phase Support:

Purpose: Luteal phase support involves hormonal medications to support the early stages of pregnancy following embryo transfer.

Procedure:

Progesterone Supplementation: Progesterone supplementation is commonly prescribed to support the luteal phase, which is crucial for maintaining the uterine lining and supporting embryo implantation.
Monitoring: Hormone levels and uterine lining thickness may be monitored through blood tests and ultrasound scans to assess the success of embryo implantation.
Continued Support: Luteal phase support may continue until pregnancy is confirmed through blood tests measuring hCG (human chorionic gonadotropin) levels, typically around two weeks after embryo transfer.

Post-operative Period of IVF with Gender Selection Procedure

Short-Term Healing Period (Immediate Post-Procedure)

Recovery Room Stay:

After embryo transfer, patients are usually observed for a brief period in a recovery room. Vital signs may be monitored to ensure stability post-procedure.

Rest and Relaxation:

Following embryo transfer, it is often recommended to rest for a short time before resuming normal activities. Some clinics advise a day of rest while others may suggest a more relaxed approach.

Activity Restrictions:

Patients are typically advised to avoid strenuous activities, heavy lifting, and excessive physical exertion immediately after embryo transfer to minimize the risk of complications.

Medication Protocol:

Continued use of medications such as progesterone supplements or other hormone medications may be prescribed to support the early stages of pregnancy and implantation.

Hydration and Diet:

Adequate hydration and a balanced diet are encouraged to support overall health and potentially enhance implantation and early embryo development.

Symptom Monitoring:

Patients may be instructed to monitor for any potential side effects or symptoms, such as mild cramping, bloating, or spotting, which are common post-procedure.

Follow-Up Appointment:

A follow-up appointment with the fertility specialist is typically scheduled within the next week to assess early pregnancy signs, review medication protocols, and discuss next steps.

Long-Term Healing Period (Post-Procedure Recovery)

Two-Week Wait:

The two-week wait refers to the period between embryo transfer and the scheduled pregnancy test. During this time, patients may experience a range of emotions and physical sensations as they await the test results.

Continued Medication Use:

Progesterone supplementation or other medications may continue to be prescribed during the two-week wait to support the luteal phase and potential pregnancy.

Emotional Support:

Emotional support and counseling services may be available to help patients cope with the emotional ups and downs of the waiting period and potential outcomes.

Pregnancy Test:

Approximately two weeks after embryo transfer, a blood test measuring hCG (human chorionic gonadotropin) levels is performed to confirm pregnancy. This test provides early indications of embryo implantation and pregnancy viability.

Ultrasound Confirmation:

If pregnancy is confirmed through the blood test, an ultrasound scan is scheduled several weeks later to confirm fetal heartbeat and assess early fetal development.

Continued Care and Monitoring:

Throughout early pregnancy, patients continue to receive care and monitoring from their fertility clinic or obstetrician. Regular appointments may include ultrasound scans, hormone level checks, and overall pregnancy health assessments.

Potential Pregnancy Complications:

Patients should be aware of potential pregnancy complications and symptoms that may require immediate medical attention, such as severe abdominal pain, heavy bleeding, or sudden changes in symptoms.

Supportive Care and Resources:

Fertility clinics often provide resources, support groups, and educational materials to assist patients throughout the pregnancy journey, addressing both physical and emotional aspects of pregnancy after IVF.

Birth Planning:

As pregnancy progresses, patients begin to plan for childbirth, including discussions with healthcare providers about prenatal care, delivery options, and postpartum care.

Conclusion

IVF with PGD for gender selection in Turkey offers a combination of affordability, high-quality medical services, and favorable success rates.

By understanding the detailed costs, factors influencing pricing, and additional considerations, patients can make informed decisions about their fertility treatment journey.

Whether it’s choosing the right clinic, understanding the legal aspects, or planning for travel and accommodation, comprehensive knowledge is key to a successful and satisfying experience.